Detalhe da pesquisa
1.
Peptidyl-tRNA hydrolase is the nascent chain release factor in bacterial ribosome-associated quality control.
Mol Cell
; 84(4): 715-726.e5, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38183984
2.
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it.
Nat Chem Biol
; 2024 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38238495
3.
Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance.
Nat Chem Biol
; 17(4): 412-420, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33462493
4.
A long-distance rRNA base pair impacts the ability of macrolide antibiotics to kill bacteria.
Proc Natl Acad Sci U S A
; 117(4): 1971-1975, 2020 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31932436
5.
High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.
RNA
; 25(5): 600-606, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30733327
6.
Ribosome-Associated Quality Control in Bacteria.
Biochemistry (Mosc)
; 86(8): 942-951, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34488571
7.
Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics.
Proc Natl Acad Sci U S A
; 114(52): 13673-13678, 2017 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229833
8.
Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins.
Nucleic Acids Res
; 45(16): 9573-9582, 2017 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934499
9.
An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance.
Science
; 383(6684): 721-726, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38359125
10.
Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Nat Commun
; 14(1): 4196, 2023 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37452045
11.
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion.
bioRxiv
; 2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37808676
12.
Attenuation-based dual-fluorescent-protein reporter for screening translation inhibitors.
Antimicrob Agents Chemother
; 56(4): 1774-83, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22252829
13.
Context-specific action of macrolide antibiotics on the eukaryotic ribosome.
Nat Commun
; 12(1): 2803, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33990576
14.
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.
Nat Commun
; 12(1): 4466, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34294725
15.
Effective cotranslational folding of firefly luciferase without chaperones of the Hsp70 family.
Protein Sci
; 15(2): 242-7, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16385000